Ovitrelle® es la única gonadotropina coriónica humana recombinante (hCG-r) y la primera aprobada en para el tratamiento de la infertilidad.
Ovitrelle® cuenta con ventajas importantes sobre los preparados existentes de hCG derivada de la orina:
Es la única hCG recombinante
Permite realizar un régimen de estimulación ovárica absolutamente recombinante
Mayor seguridad que los preparados de hCG urinaria 1, 2, 3, 4, 5
Uniformidad de lote a lote 3
Referencias:
1. Ludwig M, et al. Use of recombinant human chorionic gonadotropin in ovulation. Fertil steril 2003; 79 (5): 1051-9
2. Chang P, et al. Recombinant human chorionic gonadotropin (rhCG) in assisted reproductive technology: results of a clinical trial comparing two doses of rhCG (Ovidrel) to urinary hCG (Profasi) for induction of final follicular maturation in vitro fertilization-embryo transfer. Fertil Steril 2011; 76 (1): 67-74
3. Driscoll GL, et al. A prospective, randomized, controlled, double-blind, double-dummy comparison of recombinant and urinary HCG for inducing oocyte maturation and follicular luteinisation in ovarian stimulation. Hum Reprod 2000; 15 (6): 1305-10.
4. The European Recombinant Human Chorionic Gonadotrophin Study Grouo. Induction of final follicular maturation and early kuteinization in women ubdergoing ovulation induction for assisted reproduction treatment-recombinant HCG versus urinary HCG. Hum Reprod 2000; 15 (7): 1446-1451
5. Induction of ovulation in World Health Organization group II anovulatory women undergoing follicular stimulation with recombinant human follicle-stimulating hormone: a comparision of recombinant human chorionic gonadotropin (rhCG) and urinary hCG. Fertility and Sterility 2001; 75 (6): 1111-1118